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 | Acesso ao texto completo restrito à biblioteca da Embrapa Suínos e Aves. Para informações adicionais entre em contato com cnpsa.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Suínos e Aves. |
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Data corrente: |
15/10/2015 |
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Data da última atualização: |
15/03/2016 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
GODOY, T. F.; MOREIRA, G. C. M.; BOSCHIERO, C.; GHEYAS, A. A.; GASPARIN, G.; PADUAN, M.; ANDRADE, S. C. S.; MONTENEGRO, H.; BURT, D. W.; LEDUR, M. C.; COUTINHO, L. L. |
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Afiliação: |
THAYS FERNANDA GODOY, ESALQ; GABRIEL COSTA MONTEIRO MOREIRA, ESALQ; CLARISSA BOSCHIERO, ESALQ; ALMAS A. GHEYAS, University of Edinburgh; GUSTAVO GASPARIN, ESALQ; MARCELA PADUAN, ESALQ; SONIA CRISTINA DA SILVA ANDRADE, ESALQ; HORACIO MONTENEGRO, ESALQ; DAVID W. BURT, University of Edinburgh; MONICA CORREA LEDUR, CNPSA; LUIZ LEHMANN COUTINHO, ESALQ. |
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Título: |
SNP and INDEL detection in a QTL region on chicken chromosome 2 associated with muscle deposition. |
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Ano de publicação: |
2015 |
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Fonte/Imprenta: |
Animal Genetics, v. 6, n. 2, p. 158-163, 2015. |
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DOI: |
10.1111/age.12271 |
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Idioma: |
Inglês |
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Conteúdo: |
Genetic improvement is important for the poultry industry, contributing to increased efficiency of meat production and quality. Because breast muscle is the most valuable part of the chicken carcass, knowledge of polymorphisms influencing this trait can help breeding programs. Therefore, the complete genome of 18 chickens from two different experimental lines (broiler and layer) from EMBRAPA was sequenced, and SNPs and INDELs were detected in a QTL region for breast muscle deposition on chicken chromosome 2 between microsatellite markers MCW0185 and MCW0264 (105 849?112 649 kb). Initially, 94 674 unique SNPs and 10 448 unique INDELs were identified in the target region. After quality filtration, 77% of the SNPs (85 765) and 60% of the INDELs (7828) were retained. The studied region contains 66 genes, and functional annotation of the filtered variants identified 517 SNPs and three INDELs in exonic regions. Of these, 357 SNPs were classified as synonymous, 153 as nonsynonymous, three as stopgain, four INDELs as frameshift and three INDELs as nonframeshift. These exonic mutations were identified in 37 of the 66 genes from the target region, three of which are related to muscle development (DTNA, RB1CC1 and MOS). Fifteen non-tolerated SNPs were detected in several genes (MEP1B, PRKDC, NSMAF, TRAPPC8, SDR16C5, CHD7, ST18 and RB1CC1). These loss-of-function and exonic variants present in genes related to muscle development can be considered candidate variants for further studies in chickens. Further association studies should be performed with these candidate mutations as should validation in commercial populations to allow a better explanation of QTL effects. MenosGenetic improvement is important for the poultry industry, contributing to increased efficiency of meat production and quality. Because breast muscle is the most valuable part of the chicken carcass, knowledge of polymorphisms influencing this trait can help breeding programs. Therefore, the complete genome of 18 chickens from two different experimental lines (broiler and layer) from EMBRAPA was sequenced, and SNPs and INDELs were detected in a QTL region for breast muscle deposition on chicken chromosome 2 between microsatellite markers MCW0185 and MCW0264 (105 849?112 649 kb). Initially, 94 674 unique SNPs and 10 448 unique INDELs were identified in the target region. After quality filtration, 77% of the SNPs (85 765) and 60% of the INDELs (7828) were retained. The studied region contains 66 genes, and functional annotation of the filtered variants identified 517 SNPs and three INDELs in exonic regions. Of these, 357 SNPs were classified as synonymous, 153 as nonsynonymous, three as stopgain, four INDELs as frameshift and three INDELs as nonframeshift. These exonic mutations were identified in 37 of the 66 genes from the target region, three of which are related to muscle development (DTNA, RB1CC1 and MOS). Fifteen non-tolerated SNPs were detected in several genes (MEP1B, PRKDC, NSMAF, TRAPPC8, SDR16C5, CHD7, ST18 and RB1CC1). These loss-of-function and exonic variants present in genes related to muscle development can be considered candidate variants for further studies i... Mostrar Tudo |
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Palavras-Chave: |
Músculo de peito; SNPs. |
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Thesagro: |
Frango; Melhoramento genético animal; Mutação. |
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Thesaurus Nal: |
Animal genetics; Breast muscle; Broiler chickens; Genetic polymorphism; Quantitative trait loci; Single nucleotide polymorphism. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 02784naa a2200385 a 4500
001 2026548
005 2016-03-15
008 2015 bl uuuu u00u1 u #d
024 7 $a10.1111/age.12271$2DOI
100 1 $aGODOY, T. F.
245 $aSNP and INDEL detection in a QTL region on chicken chromosome 2 associated with muscle deposition.$h[electronic resource]
260 $c2015
520 $aGenetic improvement is important for the poultry industry, contributing to increased efficiency of meat production and quality. Because breast muscle is the most valuable part of the chicken carcass, knowledge of polymorphisms influencing this trait can help breeding programs. Therefore, the complete genome of 18 chickens from two different experimental lines (broiler and layer) from EMBRAPA was sequenced, and SNPs and INDELs were detected in a QTL region for breast muscle deposition on chicken chromosome 2 between microsatellite markers MCW0185 and MCW0264 (105 849?112 649 kb). Initially, 94 674 unique SNPs and 10 448 unique INDELs were identified in the target region. After quality filtration, 77% of the SNPs (85 765) and 60% of the INDELs (7828) were retained. The studied region contains 66 genes, and functional annotation of the filtered variants identified 517 SNPs and three INDELs in exonic regions. Of these, 357 SNPs were classified as synonymous, 153 as nonsynonymous, three as stopgain, four INDELs as frameshift and three INDELs as nonframeshift. These exonic mutations were identified in 37 of the 66 genes from the target region, three of which are related to muscle development (DTNA, RB1CC1 and MOS). Fifteen non-tolerated SNPs were detected in several genes (MEP1B, PRKDC, NSMAF, TRAPPC8, SDR16C5, CHD7, ST18 and RB1CC1). These loss-of-function and exonic variants present in genes related to muscle development can be considered candidate variants for further studies in chickens. Further association studies should be performed with these candidate mutations as should validation in commercial populations to allow a better explanation of QTL effects.
650 $aAnimal genetics
650 $aBreast muscle
650 $aBroiler chickens
650 $aGenetic polymorphism
650 $aQuantitative trait loci
650 $aSingle nucleotide polymorphism
650 $aFrango
650 $aMelhoramento genético animal
650 $aMutação
653 $aMúsculo de peito
653 $aSNPs
700 1 $aMOREIRA, G. C. M.
700 1 $aBOSCHIERO, C.
700 1 $aGHEYAS, A. A.
700 1 $aGASPARIN, G.
700 1 $aPADUAN, M.
700 1 $aANDRADE, S. C. S.
700 1 $aMONTENEGRO, H.
700 1 $aBURT, D. W.
700 1 $aLEDUR, M. C.
700 1 $aCOUTINHO, L. L.
773 $tAnimal Genetics$gv. 6, n. 2, p. 158-163, 2015.
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Registro original: |
Embrapa Suínos e Aves (CNPSA) |
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Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
URL |
Voltar
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Registro Completo
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Biblioteca(s): |
Embrapa Pantanal; Embrapa Suínos e Aves. |
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Data corrente: |
05/11/2019 |
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Data da última atualização: |
05/11/2019 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 2 |
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Autoria: |
BRAZ, P. H.; OLIVEIRA, M. R.; SILVA, V. S.; TOMAS, W. M.; JULIANO, R. S.; MOREIRA, T. A.; ZIMMERMANN, N. P.; PELLEGRIN, A. O. |
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Afiliação: |
PAULO HENRIQUE BRAZ, IFFAR; UFMS; VIRGINIA SANTIAGO SILVA, CNPSA; WALFRIDO MORAES TOMAS, CPAP; RAQUEL SOARES JULIANO, CPAP; THAMY A. MOREIRA, UFMS; NAMOR P. ZIMMERMANN, Unigran; AIESCA OLIVEIRA PELLEGRIN, CPAP. |
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Título: |
Risk of exposure of farms and subsistence nurseries to contact with wild boar in southern Mato Grosso do Sul. |
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Ano de publicação: |
2019 |
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Fonte/Imprenta: |
Pesquisa Veterinária Brasileira, v. 39, n. 2, p. 148-154, 2019. |
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DOI: |
10.1590/1678-5150-pvb-5888 |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: With the advancement of wild boar distribution in the rural environment, its impacts are not limited to health in the pig sector, but the requirements for monitoring and control of the species are requirements laid down by the OIE for the recognition of classical swine fever free zone status. The construction of ecological models of favorability or suitability for the occurrence of pest species are necessary tools for the decision making on priority areas of management aiming at risk management. This work aims to map the level of suitability for the occurrence of wild boar in the southern state of Mato Grosso do Sul, as well as to identify the main risk variables for contact with the wild boar and evaluate the biosecurity measures adopted by commercial farms integrated in the south of the State of Mato Grosso do Sul. To evaluate the risk potential of wild boar for commercial and subsistence swine farming in southern Mato Grosso do Sul, a model of environmental suitability was constructed for this species in the swine producing region. This model considered different environmental strata, being the selection of the layers considered the physiological and behavioral characteristics of the species. In parallel, interviews were carried out in a sample of commercial farms integrating the region to survey the perception of the presence of the invasive species and the biosafety measures adopted. The results of this work indicate that the risk of contact among wild boars and animals reared in closed production systems may be high in the study area and only establishment of appropriate biosecurity measures that consider the characteristics and habits of the boar may prevent the intrusion of this species and contact with domestic swine. The built model can be considered of high reliability and it is recommended to apply it to other areas of the state, being a useful tool for the productive sector, environmental agencies and decision makers. Resumo: Com o avanço da distribuição do javali no ambiente rural, seus impactos não se restringem somente a sanidade suidea, embora as exigências quanto ao monitoramento e controle da espécie sejam exigências previstas pela OIE, para o reconhecimento do status de zona livre de peste suína clássica. A construção de modelos ecológicos de favorabilidade ou adequabilidade para a ocorrência de espécies-praga são ferramentas necessárias para as tomadas de decisão sobre áreas prioritárias de manejo visando gestão de risco. Este trabalho objetiva mapear o nível de adequabilidade para a ocorrência de javalis no sul do Estado de Mato Grosso do Sul, bem como levantar as principais variáveis de risco para o contato com o javali asselvajado e avaliar as medidas de biosseguridade adotadas por granjas comerciais integradas no sul do Estado do Mato Grosso do Sul. Para avaliar o potencial de risco exercido pelos javalis para a suinocultura comercial e de subsistência nesta região foi construído um modelo de adequabilidade ambiental para essa espécie na região produtora de suínos. Esse modelo considerou diferentes estratos ambientais, sendo que para a seleção das camadas consideram-se características fisiológicas e comportamentais da espécie. Em paralelo, entrevistas foram realizadas em uma amostragem de granjas comerciais de integração da região para levantamento da percepção quanto a presença da espécie invasora e as medidas de biossegurança adotadas. Os resultados desse trabalho indicam que o risco de contato entre javalis de vida livre e os animais criados em sistemas de produção fechados pode ser alto na área de estudo e somente estabelecimento de medidas de biosseguridade apropriadas, que considerem as características e hábitos do javali poderá impedir a intrusão dessa espécie e o contato com os suínos domésticos. O modelo construído pode ser considerado de elevada confiabilidade e recomenda-se a sua aplicação para as outras áreas do estado, sendo uma ferramenta útil para o setor produtivo, os órgãos ambientais e os tomadores de decisão. MenosAbstract: With the advancement of wild boar distribution in the rural environment, its impacts are not limited to health in the pig sector, but the requirements for monitoring and control of the species are requirements laid down by the OIE for the recognition of classical swine fever free zone status. The construction of ecological models of favorability or suitability for the occurrence of pest species are necessary tools for the decision making on priority areas of management aiming at risk management. This work aims to map the level of suitability for the occurrence of wild boar in the southern state of Mato Grosso do Sul, as well as to identify the main risk variables for contact with the wild boar and evaluate the biosecurity measures adopted by commercial farms integrated in the south of the State of Mato Grosso do Sul. To evaluate the risk potential of wild boar for commercial and subsistence swine farming in southern Mato Grosso do Sul, a model of environmental suitability was constructed for this species in the swine producing region. This model considered different environmental strata, being the selection of the layers considered the physiological and behavioral characteristics of the species. In parallel, interviews were carried out in a sample of commercial farms integrating the region to survey the perception of the presence of the invasive species and the biosafety measures adopted. The results of this work indicate that the risk of contact among wild boars a... Mostrar Tudo |
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Palavras-Chave: |
Biosseguridade; Epidemiologia espacial; Landscape epidemiology; Mato Grosso do Sul. |
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Thesagro: |
Comportamento Animal; Criação; Granja; Javali. |
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Thesaurus NAL: |
Animal behavior; Animal production; Biosecurity; Farms; Swine production; Wild boars. |
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Categoria do assunto: |
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L Ciência Animal e Produtos de Origem Animal |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/204272/1/final9203.pdf
|
|
Marc: |
LEADER 05210naa a2200385 a 4500
001 2113913
005 2019-11-05
008 2019 bl uuuu u00u1 u #d
024 7 $a10.1590/1678-5150-pvb-5888$2DOI
100 1 $aBRAZ, P. H.
245 $aRisk of exposure of farms and subsistence nurseries to contact with wild boar in southern Mato Grosso do Sul.$h[electronic resource]
260 $c2019
520 $aAbstract: With the advancement of wild boar distribution in the rural environment, its impacts are not limited to health in the pig sector, but the requirements for monitoring and control of the species are requirements laid down by the OIE for the recognition of classical swine fever free zone status. The construction of ecological models of favorability or suitability for the occurrence of pest species are necessary tools for the decision making on priority areas of management aiming at risk management. This work aims to map the level of suitability for the occurrence of wild boar in the southern state of Mato Grosso do Sul, as well as to identify the main risk variables for contact with the wild boar and evaluate the biosecurity measures adopted by commercial farms integrated in the south of the State of Mato Grosso do Sul. To evaluate the risk potential of wild boar for commercial and subsistence swine farming in southern Mato Grosso do Sul, a model of environmental suitability was constructed for this species in the swine producing region. This model considered different environmental strata, being the selection of the layers considered the physiological and behavioral characteristics of the species. In parallel, interviews were carried out in a sample of commercial farms integrating the region to survey the perception of the presence of the invasive species and the biosafety measures adopted. The results of this work indicate that the risk of contact among wild boars and animals reared in closed production systems may be high in the study area and only establishment of appropriate biosecurity measures that consider the characteristics and habits of the boar may prevent the intrusion of this species and contact with domestic swine. The built model can be considered of high reliability and it is recommended to apply it to other areas of the state, being a useful tool for the productive sector, environmental agencies and decision makers. Resumo: Com o avanço da distribuição do javali no ambiente rural, seus impactos não se restringem somente a sanidade suidea, embora as exigências quanto ao monitoramento e controle da espécie sejam exigências previstas pela OIE, para o reconhecimento do status de zona livre de peste suína clássica. A construção de modelos ecológicos de favorabilidade ou adequabilidade para a ocorrência de espécies-praga são ferramentas necessárias para as tomadas de decisão sobre áreas prioritárias de manejo visando gestão de risco. Este trabalho objetiva mapear o nível de adequabilidade para a ocorrência de javalis no sul do Estado de Mato Grosso do Sul, bem como levantar as principais variáveis de risco para o contato com o javali asselvajado e avaliar as medidas de biosseguridade adotadas por granjas comerciais integradas no sul do Estado do Mato Grosso do Sul. Para avaliar o potencial de risco exercido pelos javalis para a suinocultura comercial e de subsistência nesta região foi construído um modelo de adequabilidade ambiental para essa espécie na região produtora de suínos. Esse modelo considerou diferentes estratos ambientais, sendo que para a seleção das camadas consideram-se características fisiológicas e comportamentais da espécie. Em paralelo, entrevistas foram realizadas em uma amostragem de granjas comerciais de integração da região para levantamento da percepção quanto a presença da espécie invasora e as medidas de biossegurança adotadas. Os resultados desse trabalho indicam que o risco de contato entre javalis de vida livre e os animais criados em sistemas de produção fechados pode ser alto na área de estudo e somente estabelecimento de medidas de biosseguridade apropriadas, que considerem as características e hábitos do javali poderá impedir a intrusão dessa espécie e o contato com os suínos domésticos. O modelo construído pode ser considerado de elevada confiabilidade e recomenda-se a sua aplicação para as outras áreas do estado, sendo uma ferramenta útil para o setor produtivo, os órgãos ambientais e os tomadores de decisão.
650 $aAnimal behavior
650 $aAnimal production
650 $aBiosecurity
650 $aFarms
650 $aSwine production
650 $aWild boars
650 $aComportamento Animal
650 $aCriação
650 $aGranja
650 $aJavali
653 $aBiosseguridade
653 $aEpidemiologia espacial
653 $aLandscape epidemiology
653 $aMato Grosso do Sul
700 1 $aOLIVEIRA, M. R.
700 1 $aSILVA, V. S.
700 1 $aTOMAS, W. M.
700 1 $aJULIANO, R. S.
700 1 $aMOREIRA, T. A.
700 1 $aZIMMERMANN, N. P.
700 1 $aPELLEGRIN, A. O.
773 $tPesquisa Veterinária Brasileira$gv. 39, n. 2, p. 148-154, 2019.
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Embrapa Suínos e Aves (CNPSA) |
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